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Biotechnology to France

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(Last updated: 20 Dec 2010)

Trends and opportunities

The market

France has the fifth largest market share of the biotechnology industry in Europe. One of the key strengths of the French biotechnology industry is the number of research institutions, technology parks and scientific personnel active in the industry. This has facilitated technology transfer from academic institutions to the private sector, which is a key component of the French industry.

France’s regulatory environment is considered one of the most transparent in the world, based on European Union (EU) directives. French law also provides tax credits and other financial mechanisms to encourage innovation in biotechnology through research-driven start-ups. Government regulations within the EU, however are quite strict and often require lengthy and costly trials of new products.

In 2004, the French Government launched an initiative to encourage local and regional cooperation to support industry growth. Five thousand organisations came together to form 71 centres of excellence in specific geographic locations to facilitate collaboration within specialised industries. Among these were seven biopoles (biotechnology centres).

Each individual cluster focuses on specific activities:

  • Lyon BioPole (Rhône-Alpes): infectious diseases, vaccines and diagnostics (World dimension)
  • Medicen Paris Region (île de France): neurology, cancer, CNS, infectious diseases, imaging, molecular and cellular therapies, drug development
  • Nutrition Santé Longévité (Nord Pas de Calais): nutrition, healthcare and longevity
  • Atlantic Biothérapies (Pays de la Loire): biotherapy, biodiagnostics
  • Alsace Biovalley (Alsace): genomics, drugs, non-invasive surgery, medical devices
  • CancerBioSanté (Midi-Pyrénées, Limousin): cancer
  • Orphème (PACA, Languedoc-Roussillon): emerging pathologies and orphan diseases

In addition to these biopoles, there are eight genopoles specialising in genomics and post-genomics research. These genopoles bring together biotechnology companies, large public laboratories, university laboratories and advanced teaching in the fields of genomics and biology. They aim to encourage large-scale and cross-disciplinary research in projects in biological sciences and foster innovation.

They are located in:

  • Evry/Ile de France
  • Montpellier and Perpignan/Languedoc Roussillon
  • Lille/Nord Pas de Calais
  • Lyon and Grenoble/Rhône-Alpes
  • Marseille & Nice/PACA
  • Strasbourg/Alsace-Lorraine
  • Toulouse/Midi-Pyrénées (Toulouse has also developed Agrobiopole, a 300-hectare complex focusing on agricultural biotechnology, as part of the region’s biotechnology strategy)
  • Rennes and Nantes/Ouest

Opportunities

Specific opportunities for Australian biotechnology companies include:

  • Drug discovery and development – opportunity to initiate collaborative research partnerships, technology transfer agreements or licensing ventures.
  • Companies with product commercialisation, business and financial expertise to partner with early stage research companies and institutions.
  • Biotech products related to animal food, vegetal production and environment are minimally investigated by French companies and Australian companies could therefore find opportunities for these types of products.
  • Potential for generics market growth in France is considerable.

Competitive environment

The French biotechnology industry is dominated by small and medium-sized enterprises, accounting for 80 per cent of the companies. There are also a number of leading multinationals active in the market including Sanofi-Aventis, Roche Diagnostics and Pfizer.

The dominant French companies in the market include LFB, Ethypharm Group, CEREP, Flamel Technologies, Rhobio, Genfit, NicOx, Transgene and Eurofins.

Australia has a strong international reputation for its quality of science and as a source of intellectual capital. Several French biotechnology and biotechnology application companies have invested in Australia, and CSIRO has its European research centre in Montpellier. Australia’s expertise in stem cell research and overall biodiversity is recognised by leading French research organisations and the biotechnology industry.

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Tariffs, regulations and customs

All European Union (EU) countries are covered by a harmonised trade system. Common Customs Tariff (CCT) is applicable to goods from non-EU countries, including Australia. Goods travelling between EU countries member states are free of customs duty. Most duties are ad valorem (%), based on the GATT Valuation Code (approximate CIF value).

Certain products will need to comply with pan-European legislation for medical devices, medicines, foods and ingredients. There are also local variations in legislation, packaging and labelling that need careful consideration before shipping samples or final products.

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Marketing your products and services

Market entry

The main methods of market entry for biotechnology companies looking at France are:

  • Supply of products or raw materials
  • Collaborative research partnerships with French company/institution
  • Investment into France

Supplying to a European company is the traditional market entry strategy and a good option to consider for companies with products that can be easily combined by French end-users. Pharmaceutical companies are likely to be a major end-user. You can develop relationships with these companies via licensing, sales, contracting or R&D services.

Collaborating with French biotechnology/pharmaceutical companies and research institutions, often in the development phase. These relationships can take the form of:

  • Technology transfers
  • Licensing agreements
  • Co-development (platform development through to product pipeline)
  • Co-marketing
  • Capital risk investment (this is entirely private in France)

Investing in France may be necessary in order to gain access to venture capital funding or research collaborations. This could take the form of setting up a branch of your company overseas, or acquiring a suitable French company.

Attending the yearly fair EuroBio in Lille and Paris is also a good way to meet bioscience and bioindustry stakeholders from Europe and across the world.

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Links and industry contacts

Biotechnology–related resources

Actinbiotech – www.actinbiotech.com
Alsace BioValley Association – www.biovalley.com
Biotech Industry Database – http://biotech.education.fr
Biotech in France – www.france-biotech.org/TEMPLATES/HOMEPAGE_UK.asp
BioCentury – www.biocentury.com
BiotechInfo – www.biotechinfo.fr
EuropaBio – www.europabio.org
European bio-based economy website – www.bio-economy.net
French Biotech and Bio-industry Association – www.adebio.org
Leem – www.leem.org
Pharmaceutiques – www.pharmaceutiques.com
Recap – www.recap.com
Veille Biotech – www.info-veille-biotech.com

Biopole and genopole websites

Accompagnement porteurs projets & création (ACCEVAL) – www.acceval-irhn.com
Agence pour le Développement Economique de la Région Lyonnaise (ADERLY) – www.aderly.com
Angers Technopole – www.angerstechnopole.org
Atlanpole – www.atlanpole.fr
Atlantic Biothérapies – www.atlantic-biotherapies.com
Bio Incubateur Eurasanté – www.eurasante.com
Biotech Santé – www.parisbiotechsante.org
Bioparc – www.bioparc.com
BiotechNîmes – www.biotechnimes.org
Centre Européen d'Entreprise et d'Innovation de Montpellier Agglomération – www.montpellier-technopole.com
Genopole – www.genopole.fr
Genopole Evry – www.genopole.org
Grenoble Alpes Incubation (GRAIN) – www.grain-incubation.com
Impulse (Incubateur Aix-Marseille-Avignon) M.D.I. – www.incubateur-impulse.com
Incubateur Midi-Pyrénées – www.incubateurmipy.com
Incubateur Régional Poitou-charentes (IRPC) – www.irpc.asso.fr
Lille-Nord Pas de Calais Genopole – www.genopole-lille.fr
Languedoc-Roussillon Incubation (LRI) – www.lr-incubation.com
LyonBioPole – www.lyonbiopole.org
Marseille-Nice Genopole – www.genopole.univ-mrs.fr
Medicen Paris – www.medicen.org
Montpellier-Languedoc-Roussillon Génopole – www.genopole-montpellier-lr.org
Normandie Incubation – www.normandie-incubation.com
Nutrition Santé Longetivité – www.eurasante.com
Orphème – www.orpheme.org
Ouest Genopole – www.ouest-genopole.org
Pasteur Genopole – www.pasteur.fr/recherche/genopole
Rhone-Alpes Genopole – www.rhone-alpes-genopole.com
Strasbourg Innovations Thérapeutiques – www.innovations-therapeutiques.fr
Toulouse-Midi-Pyrénées Genopole – http://genopole-toulouse.prd.fr
Toulouse Cancer BioSanté – www.canceropole-toulouse.com

Research centres

Curie Institute – www.curie.fr
National Institute for Agricultural Research – www.inra.fr
National Institute for Health and Medical Research – www.inserm.fr
National Science Research Centre – www.cnrs.fr
Pasteur Institute – www.pasteur.fr

Government, business and trade resources for France

Invest in France – www.investinfrance.org

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Contact details

The Australian Trade Commission – Austrade – is the Australian Government’s trade and investment development agency.

Through Austrade’s network of offices in over 50 countries, we assist Australian companies to succeed in international business, attract productive foreign direct investment into Australia and promote Australia's education sector internationally.

For more information on how Austrade can assist you, contact us on:

Australia ph: 13 28 78 | Email: info@austrade.gov.au

A list of Austrade offices (in alphabetical order of country) is also available.

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